紅斑性狼瘡治療總整理(缺鎂鋅硒錳維它命A維它命D,可以喝草莓亞培安素或桂格特級完膳)
告訴我們:
SLE患者的平均紅細胞(RBC)鎂(Mg)水平顯著低於參考對照。
與健康對照相比,SLE患者的Alb(白蛋白),Zn(鋅),Se(硒)血清值較低
SLE患者(n = 27)的血清中銅藍蛋白(Cp)和銅(Cu)
水平較高,而運鐵蛋白(transferrin,Trf),白蛋白(Alb),鋅(Zn),
鎂(Mg),錳(Mn)和鐵(Fe)水平較低。
systemic lupus erythematosus (SLE)
系統性紅斑狼瘡(SLE)
IL-2 deficiency results in systemic dysregulation of host immune responses in patients suffering from SLE disease.
IL-2缺乏導致患有SLE疾病的患者的全身免疫反應異常。
The level of ex vivo IFN-γ production was significantly lower in patients with active systemic lupus erythematosus (SLE) (n = 64) than in those with inactive SLE (n = 54)(median 0.92 vs. 11.06 IU/mL, p < 0.001).
積極性系統性狼瘡患者比那些非積極性SLE的IFN-γ產生水平顯著降低
Further, plasma IL-4 concentrations were significantly lower in SLE patients
than in healthy controls (1.59 3.53 versus 5.67 11.28 pg/ml, p ¼ 0.042).
此外,SLE患者的血漿IL-4濃度顯著低於健康對照組
IL-4 synergizes with low-dose IL-2 to restore systemic lupus erythematosus B cells
at the resting naive status
IL-4與低劑量IL-2協同作用,使系統性紅斑狼瘡B細胞恢復到靜止的幼稚狀態
We have recently identified that down-regulation of interleukin-4 receptor (IL-4R)
is a novel hallmark of B-cell dysregulation in SLE patients.
我們最近發現白細胞介素4受體(IL-4R)的下調是SLE患者B細胞功能異常的新標誌。
小結1:
由以上可知,紅斑性狼瘡患者缺少IL-4、IL-2、IFN-r。